Mast Cell Activation Disorder

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Mast cell activation disorder/syndrome (MCAD/MCAS)

A disorder or syndrome in which there is evidence of the systemic, inappropriate release of mast cell mediators. While people with MCAD/MCAS have a normal or near-normal tryptase level and a bone marrow biopsy that contains a normal number of mast cells, they experience most of the same symptoms as does someone with mastocytosis.